DPCstruct | MC35181

Metacluster Properties and Pfam Annotations

Number of structural domains350
Mean domain length (aa)104 ± 15 aa
Standard deviation of domain lengths15.14
Length coefficient of variation0.15
Mean AlphaFold2 pLDDT confidence score78.87
Mean fraction of residues predicted as intrinsically disordered0.21
Mean length-normalized TM-Score0.69
Mean intra-cluster local Distance Difference Test score0.68
Mean intra-cluster sequence similarity (%)21.91
Pfam Score94.11
Assigned Pfam label(s) PF19418- CL0029- CL0123- PF01151- PF12316

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A814IRD8 637-756 None
A0A224YRQ3 825-924 None
A0A068S3M1 119-233 None
A0A7S0T3R9 38-150 None
Q4PE51 1348-1446 None
A0A6H5K2H7 7-96 None
A0A6B2KXG8 653-752 None
A0A0J8RMP0 110-217 None
A0A5J5DA23 9-130 None
A0A6I9XIW4 111-223 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.