DPCstruct | MC35181

Metacluster Properties and Pfam Annotations

Number of structural domains350
Mean domain length (aa)104 ± 15 aa
Standard deviation of domain lengths15.14
Length coefficient of variation0.15
Mean AlphaFold2 pLDDT confidence score78.87
Mean fraction of residues predicted as intrinsically disordered0.21
Mean length-normalized TM-Score0.69
Mean intra-cluster local Distance Difference Test score0.68
Mean intra-cluster sequence similarity (%)21.91
Pfam Score94.11
Assigned Pfam label(s) PF19418- CL0029- CL0123- PF01151- PF12316

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A7R9CFH5 6-101 None
A0A182SXS2 69-178 None
A0A1I8CVZ3 422-558 None
A0A267H6I0 514-616 None
A0A3Q2U8J4 3-80 None
A0A0R3SJJ9 170-273 None
A0A1I8CQA4 19-136 None
A0A401PUA9 393-498 None
A0A1I8CRY2 359-478 None
A0A1I8CRJ1 303-393 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.