DPCstruct | MC35181

Metacluster Properties and Pfam Annotations

Number of structural domains350
Mean domain length (aa)104 ± 15 aa
Standard deviation of domain lengths15.14
Length coefficient of variation0.15
Mean AlphaFold2 pLDDT confidence score78.87
Mean fraction of residues predicted as intrinsically disordered0.21
Mean length-normalized TM-Score0.69
Mean intra-cluster local Distance Difference Test score0.68
Mean intra-cluster sequence similarity (%)21.91
Pfam Score94.11
Assigned Pfam label(s) PF19418- CL0029- CL0123- PF01151- PF12316

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
Q22TX5 446-552 None
A0A2U1KI95 718-797 None
A0A367K5Y1 155-259 None
A0A183I854 23-132 None
A0A7J8E464 1-88 None
A0A1X7VB84 358-465 None
A0A820VCS9 84-182 None
A0A7S3WW31 12-96 None
A0A0K2UEV6 9-121 None
A0A094EEF7 78-193 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.