DPCstruct | MC35181

Metacluster Properties and Pfam Annotations

Number of structural domains350
Mean domain length (aa)104 ± 15 aa
Standard deviation of domain lengths15.14
Length coefficient of variation0.15
Mean AlphaFold2 pLDDT confidence score78.87
Mean fraction of residues predicted as intrinsically disordered0.21
Mean length-normalized TM-Score0.69
Mean intra-cluster local Distance Difference Test score0.68
Mean intra-cluster sequence similarity (%)21.91
Pfam Score94.11
Assigned Pfam label(s) PF19418- CL0029- CL0123- PF01151- PF12316

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A5J4NLI6 295-399 None
A0A251RMK0 23-110 None
A0A2H2JJ34 186-306 None
L8HA90 68-189 None
T1EFK9 203-291 None
U5DND5 99-180 None
A4RZ44 63-161 None
A0A7J7F4Z8 120-236 None
A0A2P8Z9U2 197-290 None
A0A665VKQ9 314-388 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.