DPCstruct | MC35181

Metacluster Properties and Pfam Annotations

Number of structural domains350
Mean domain length (aa)104 ± 15 aa
Standard deviation of domain lengths15.14
Length coefficient of variation0.15
Mean AlphaFold2 pLDDT confidence score78.87
Mean fraction of residues predicted as intrinsically disordered0.21
Mean length-normalized TM-Score0.69
Mean intra-cluster local Distance Difference Test score0.68
Mean intra-cluster sequence similarity (%)21.91
Pfam Score94.11
Assigned Pfam label(s) PF19418- CL0029- CL0123- PF01151- PF12316

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A7R9I3I9 253-353 None
I4DQ67 1-61 None
Q5R473 205-297 None
A0A4X2LTF5 210-317 None
A0A6P8GZ55 35-132 None
A0A1A8B9G9 3-90 None
W6UHR7 12-102 None
A0A674AN73 375-477 None
L0P6Z8 454-551 None
A0A0N5CB54 24-160 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.