DPCstruct | MC13453

Metacluster Properties and Pfam Annotations

Number of structural domains233
Mean domain length (aa)134 ± 23 aa
Standard deviation of domain lengths22.79
Length coefficient of variation0.17
Mean AlphaFold2 pLDDT confidence score77.46
Mean fraction of residues predicted as intrinsically disordered0.24
Mean length-normalized TM-Score0.63
Mean intra-cluster local Distance Difference Test score0.71
Mean intra-cluster sequence similarity (%)35.64
Pfam Score91.41
Assigned Pfam label(s) CL0264- PF14416- CL0016- CL0650- CL0133

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A2K3N492 108-240 None
A0A0J8B5B2 13-143 None
A0A5C7HE63 665-778 None
A0A6L5B708 30-196 None
A0A0R0LFB2 41-139 None
A0A6A2YZW6 198-355 None
A0A0D3EL38 21-165 None
W1P7N3 45-171 None
A0A314LF74 33-154 None
A0A3B6EIQ8 17-169 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.