DPCstruct | MC13453

Metacluster Properties and Pfam Annotations

Number of structural domains233
Mean domain length (aa)134 ± 23 aa
Standard deviation of domain lengths22.79
Length coefficient of variation0.17
Mean AlphaFold2 pLDDT confidence score77.46
Mean fraction of residues predicted as intrinsically disordered0.24
Mean length-normalized TM-Score0.63
Mean intra-cluster local Distance Difference Test score0.71
Mean intra-cluster sequence similarity (%)35.64
Pfam Score91.41
Assigned Pfam label(s) CL0264- PF14416- CL0016- CL0650- CL0133

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A2C9MA65 142-266 None
A0A6A6K6N4 8-152 None
A0A6A6KNT7 384-505 None
A0A287P5M6 1-106 None
A0A2U1KGZ1 208-316 None
V7AY30 91-247 None
M4EW55 538-695 None
A0A444GCT4 34-179 None
A0A444D7B1 37-166 None
A0A2K3MCS5 5-119 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.