DPCstruct | MC59596

Metacluster Properties and Pfam Annotations

Number of structural domains846
Mean domain length (aa)204 ± 35 aa
Standard deviation of domain lengths35.34
Length coefficient of variation0.17
Mean AlphaFold2 pLDDT confidence score83.56
Mean fraction of residues predicted as intrinsically disordered0.24
Mean length-normalized TM-Score0.55
Mean intra-cluster local Distance Difference Test score0.53
Mean intra-cluster sequence similarity (%)18.33
Pfam Score98.16
Assigned Pfam label(s) CL0214- PF03647- PF00183- CL0207- CL0172

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
U6L292 5-189 None
A0A5C5ZHW9 18-237 None
H2AVU1 33-255 None
I5AW25 15-229 None
A0A1Y1UXF5 232-437 None
A0A1X2IPZ7 98-280 None
A0A812Y423 262-469 None
A0A835XV54 693-888 None
A0A835YBF2 12-320 None
A0A4S4DP75 89-244 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.