DPCstruct | MC59596

Metacluster Properties and Pfam Annotations

Number of structural domains846
Mean domain length (aa)204 ± 35 aa
Standard deviation of domain lengths35.34
Length coefficient of variation0.17
Mean AlphaFold2 pLDDT confidence score83.56
Mean fraction of residues predicted as intrinsically disordered0.24
Mean length-normalized TM-Score0.55
Mean intra-cluster local Distance Difference Test score0.53
Mean intra-cluster sequence similarity (%)18.33
Pfam Score98.16
Assigned Pfam label(s) CL0214- PF03647- PF00183- CL0207- CL0172

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A2D6WUM3 10-205 TIGLIILMMLAFVMIAAQPTETQEHALNEFGFSKATFLEKPWTPITSIFLHADLVHLLSNILVLLFFGMAVESEMGDKKYLAIFFLA…
A0A378WKL1 12-173 DWVLAPQFVAQGQWIRVLGSGFLHYGPLHLVVNMFALYILGRDTELVLGRSRFLAIYLVSLLGGSAAVMWLATDSATAGASGAIYGL…
A0A1S8VZ12 237-415 None
A0A7H5EXS4 7-272 None
A0A0D2PAY8 81-350 None
A0A1S8VZN5 213-428 None
A0A1Q9CB11 108-315 None
A0A800M7Z5 21-230 None
A0A2N5YTC8 4-128 None
K6DRS8 18-189 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.