DPCstruct | MC59010

Metacluster Properties and Pfam Annotations

Number of structural domains162
Mean domain length (aa)464 ± 132 aa
Standard deviation of domain lengths131.85
Length coefficient of variation0.28
Mean AlphaFold2 pLDDT confidence score75.76
Mean fraction of residues predicted as intrinsically disordered0.25
Mean length-normalized TM-Score0.44
Mean intra-cluster local Distance Difference Test score0.48
Mean intra-cluster sequence similarity (%)13.90
Pfam Score91.46
Assigned Pfam label(s) CL0220- CL0307- PF01294

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A024GHI1 193-902 None
A0A7S3UFF0 1-423 None
A0A453RE11 29-391 None
I0YKQ1 11-400 None
H6RR22 185-642 None
B5YMB2 234-778 None
C7D1W2 4-582 None
A0A847J9G5 21-454 None
C1GR52 1017-1601 None
A0A812VF39 72-540 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.