DPCstruct | MC5678

Metacluster Properties and Pfam Annotations

Number of structural domains57
Mean domain length (aa)149 ± 17 aa
Standard deviation of domain lengths16.94
Length coefficient of variation0.11
Mean AlphaFold2 pLDDT confidence score85.84
Mean fraction of residues predicted as intrinsically disordered0.31
Mean length-normalized TM-Score0.68
Mean intra-cluster local Distance Difference Test score0.70
Mean intra-cluster sequence similarity (%)23.86
Pfam Score87.27
Assigned Pfam label(s) PF00571- CL0436

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
T2IXS6 18-163 DVINKQLLIFLEAKNYEAAKTLLIPVASVDIAEAIADLPKTMQIIAFRLLNKQEAIEVYKYLDKATQQSLIEDFKDTEAVEIINNMS…
A0A6G9YRH4 330-491 ARLRGLKPAQIADLLEDADKHERGEILDQVHGDPELEADVFEELDSDESSRLLNDMPDDEVAALLGRMRADDAADSIMELRQSRRRR…
A0A7C5I4Q5 2-144 None
D6PE45 6-147 None
A0A6J6NSP4 21-171 None
A0A820TIG4 178-343 None
A0A2Z5QLG0 171-307 None
A0A535RZ74 3-182 None
A0A7R8WR58 257-407 None
A0A7X1GMK4 275-431 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.