DPCstruct | MC5678

Metacluster Properties and Pfam Annotations

Number of structural domains57
Mean domain length (aa)149 ± 17 aa
Standard deviation of domain lengths16.94
Length coefficient of variation0.11
Mean AlphaFold2 pLDDT confidence score85.84
Mean fraction of residues predicted as intrinsically disordered0.31
Mean length-normalized TM-Score0.68
Mean intra-cluster local Distance Difference Test score0.70
Mean intra-cluster sequence similarity (%)23.86
Pfam Score87.27
Assigned Pfam label(s) PF00571- CL0436

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A1Q6NYI6 2-163 None
A0A1I4VQI9 1-189 None
A0A3P8ME04 9-156 None
A0A090QU46 6-136 None
A0A0J9TKP2 269-434 None
A0A4R4ADS3 2-147 None
H3RG47 24-194 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.