DPCstruct | MC55685

Metacluster Properties and Pfam Annotations

Number of structural domains596
Mean domain length (aa)156 ± 31 aa
Standard deviation of domain lengths31.02
Length coefficient of variation0.20
Mean AlphaFold2 pLDDT confidence score80.18
Mean fraction of residues predicted as intrinsically disordered0.24
Mean length-normalized TM-Score0.55
Mean intra-cluster local Distance Difference Test score0.57
Mean intra-cluster sequence similarity (%)14.74
Pfam Score94.01
Assigned Pfam label(s) CL0489- CL0039- CL0010- CL0229- PF01448

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A225VC63 1-130 None
A0A5N5NBJ4 63-231 None
A0A7H9HTY7 87-239 None
E3LAA2 51-191 None
Q62901 38-292 None
A0A4V1J377 310-446 None
A0A6A4ZX89 157-264 None
A0A182SV47 645-781 None
A0A0C2ERC2 410-550 None
A0A5C3NMJ2 40-218 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.