DPCstruct | MC55685

Metacluster Properties and Pfam Annotations

Number of structural domains596
Mean domain length (aa)156 ± 31 aa
Standard deviation of domain lengths31.02
Length coefficient of variation0.20
Mean AlphaFold2 pLDDT confidence score80.18
Mean fraction of residues predicted as intrinsically disordered0.24
Mean length-normalized TM-Score0.55
Mean intra-cluster local Distance Difference Test score0.57
Mean intra-cluster sequence similarity (%)14.74
Pfam Score94.01
Assigned Pfam label(s) CL0489- CL0039- CL0010- CL0229- PF01448

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A0S7IF26 75-263 None
A0A6A5YIZ8 238-394 None
A0A498KBN7 1-216 None
E2A1A2 11-127 None
A0A2V3J4G4 18-224 None
A0A3R6ZZY8 35-158 None
A0A1Y1I2Q9 74-217 None
A0A2C5YUM8 41-216 None
A0A1B0FER6 528-701 None
A0A0N4URK8 230-463 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.