DPCstruct | MC55685

Metacluster Properties and Pfam Annotations

Number of structural domains596
Mean domain length (aa)156 ± 31 aa
Standard deviation of domain lengths31.02
Length coefficient of variation0.20
Mean AlphaFold2 pLDDT confidence score80.18
Mean fraction of residues predicted as intrinsically disordered0.24
Mean length-normalized TM-Score0.55
Mean intra-cluster local Distance Difference Test score0.57
Mean intra-cluster sequence similarity (%)14.74
Pfam Score94.01
Assigned Pfam label(s) CL0489- CL0039- CL0010- CL0229- PF01448

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A5A8E1U9 25-206 DASPDARPTASAVVGVPAFQWLGRGKRRGGVTEYRGFRADTHFVALGDVVMLDPGPGESEPFVGWVTRLFEASDGQMMMRAQWFFRK…
A0A830B7Y0 7-120 GKKDLDSYTIKGTNKVVRPGDCVLMRPSDTDKPPYVACVEKIEADHRNNAKVRVRWYYRPEESIGGRRQFHGAKELFLSNHFDIQSA…
A0A0C2M1M6 1-195 None
A0A068UM41 71-239 None
A0A4Z2HG55 873-1041 None
A0A1A7Y1F1 995-1158 None
A0A2G8L7C6 53-194 None
A0A2G8LJQ7 2-118 None
A0A068UPH6 22-154 None
A0A0D8XGD2 41-201 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.