DPCstruct | MC55685

Metacluster Properties and Pfam Annotations

Number of structural domains596
Mean domain length (aa)156 ± 31 aa
Standard deviation of domain lengths31.02
Length coefficient of variation0.20
Mean AlphaFold2 pLDDT confidence score80.18
Mean fraction of residues predicted as intrinsically disordered0.24
Mean length-normalized TM-Score0.55
Mean intra-cluster local Distance Difference Test score0.57
Mean intra-cluster sequence similarity (%)14.74
Pfam Score94.01
Assigned Pfam label(s) CL0489- CL0039- CL0010- CL0229- PF01448

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A1S8VY16 8-140 None
A0A2N9IE36 374-502 None
A0A4V3SII3 150-289 None
A0A4V3SIJ0 377-479 None
K8F0Z9 28-188 None
K3WTV5 268-394 None
A0A162N0X2 369-510 None
K8EGY2 409-590 None
A0A6A4Q4W0 23-181 None
A0A7J0FSL0 199-342 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.