DPCstruct | MC52077

Metacluster Properties and Pfam Annotations

Number of structural domains535
Mean domain length (aa)175 ± 45 aa
Standard deviation of domain lengths44.76
Length coefficient of variation0.26
Mean AlphaFold2 pLDDT confidence score88.43
Mean fraction of residues predicted as intrinsically disordered0.22
Mean length-normalized TM-Score0.56
Mean intra-cluster local Distance Difference Test score0.52
Mean intra-cluster sequence similarity (%)17.32
Pfam Score99.29
Assigned Pfam label(s) CL0023- PF01425- CL0269- PF00857

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
E2A8N4 329-554 None
D2R2J3 316-580 None
A0A523FSV3 35-253 None
A0A1E3Q7V6 5-126 None
A0A2T1HRS5 23-159 None
M7SVA8 15-247 None
A0A2N5N8R4 3-187 None
A0A535F5E5 2-167 None
A0A0C2EV52 19-275 None
A0A349PHR3 29-220 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.