DPCstruct | MC52077

Metacluster Properties and Pfam Annotations

Number of structural domains535
Mean domain length (aa)175 ± 45 aa
Standard deviation of domain lengths44.76
Length coefficient of variation0.26
Mean AlphaFold2 pLDDT confidence score88.43
Mean fraction of residues predicted as intrinsically disordered0.22
Mean length-normalized TM-Score0.56
Mean intra-cluster local Distance Difference Test score0.52
Mean intra-cluster sequence similarity (%)17.32
Pfam Score99.29
Assigned Pfam label(s) CL0023- PF01425- CL0269- PF00857

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A5C4VHU8 193-353 None
A0A536ATM2 4-172 None
A0A3Q7GKH4 357-542 None
A0A2C9L7J6 5-162 None
A0A1I8BD37 303-451 None
A0A7C4FMY6 269-437 None
A0A0D1XXV6 20-282 None
A0A0E2IQN7 3-116 None
A0A0C4DS93 14-264 None
A0A0T7LHZ8 126-308 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.