DPCstruct | MC50949

Metacluster Properties and Pfam Annotations

Number of structural domains538
Mean domain length (aa)226 ± 50 aa
Standard deviation of domain lengths50.35
Length coefficient of variation0.22
Mean AlphaFold2 pLDDT confidence score85.21
Mean fraction of residues predicted as intrinsically disordered0.22
Mean length-normalized TM-Score0.48
Mean intra-cluster local Distance Difference Test score0.45
Mean intra-cluster sequence similarity (%)13.04
Pfam Score97.35
Assigned Pfam label(s) CL0094- CL0015- CL0240- CL0523- CL0186

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A4V6RY12 329-523 None
A0A7S1YUI2 389-688 None
A0A6V2A725 52-241 None
A0A1Y1W5L9 268-541 None
A0A1Y1VZU4 295-483 None
A0A5H2Z9U1 5-171 None
A0A6V7U7Z7 186-399 None
A0A6V7TMJ9 17-233 None
A0A182JIZ5 133-452 None
A0A2H2HUT9 10-223 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.