DPCstruct | MC50949

Metacluster Properties and Pfam Annotations

Number of structural domains538
Mean domain length (aa)226 ± 50 aa
Standard deviation of domain lengths50.35
Length coefficient of variation0.22
Mean AlphaFold2 pLDDT confidence score85.21
Mean fraction of residues predicted as intrinsically disordered0.22
Mean length-normalized TM-Score0.48
Mean intra-cluster local Distance Difference Test score0.45
Mean intra-cluster sequence similarity (%)13.04
Pfam Score97.35
Assigned Pfam label(s) CL0094- CL0015- CL0240- CL0523- CL0186

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A658Y700 21-255 IAAALPQDEKLITGQLDNDLRYMIYPHAHPKDQVNLWLQIHTGSLQEEDNERGVAHFVEHMMFNGTKTWPGNKVIETFESMGLRFGR…
A0A535EWJ2 29-243 DRAGEMVGARTRLLAAQNGSGYTPAPSPLLKPGIAFLNKKTEQAHICLGTRAISYLDDDRYALDLINTILGEGMSSRLFLEIREKRG…
S0F6G1 27-220 None
A0A7S0LYJ5 38-239 None
F4Q925 575-864 None
A0A401FNG7 72-288 None
L5KC83 12-218 None
A0A7C4T888 263-485 None
A0A820DLA9 31-231 None
A0A0D8XHG5 219-440 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.