DPCstruct | MC50945

Metacluster Properties and Pfam Annotations

Number of structural domains603
Mean domain length (aa)267 ± 53 aa
Standard deviation of domain lengths53.44
Length coefficient of variation0.20
Mean AlphaFold2 pLDDT confidence score82.26
Mean fraction of residues predicted as intrinsically disordered0.23
Mean length-normalized TM-Score0.55
Mean intra-cluster local Distance Difference Test score0.50
Mean intra-cluster sequence similarity (%)18.51
Pfam Score98.69
Assigned Pfam label(s) CL0745- CL0125- CL0167- CL0202

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A0J0XDN4 226-640 None
A0A350Y5L4 265-533 None
A0A3F2RD22 9-258 None
A0A1R2CRT5 85-415 None
A0A5J4UNH9 2-207 None
A0A5J4V3B9 4-168 None
A0A5J4V5Z7 4-212 None
A0A498MZB5 55-334 None
D8LK54 58-340 None
D8LKI3 98-468 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.