DPCstruct | MC4961

Metacluster Properties and Pfam Annotations

Number of structural domains226
Mean domain length (aa)225 ± 29 aa
Standard deviation of domain lengths29.23
Length coefficient of variation0.13
Mean AlphaFold2 pLDDT confidence score74.18
Mean fraction of residues predicted as intrinsically disordered0.25
Mean length-normalized TM-Score0.55
Mean intra-cluster local Distance Difference Test score0.57
Mean intra-cluster sequence similarity (%)18.15
Pfam Score99.49
Assigned Pfam label(s) PF06695- PF09335

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A7J8WVI6 3-153 ELMPLIKWEMATFSTPMLAVLIFASVALFPTIFLPSSPSMWVAGMAFGYGFGFLLIISAAAVGVSLPFFIGSLFLHRIRGWLEKYPK…
I4C8Q1 6-229 ILVLLLVGLVAGIIIWGVSLPSVRQHMLTVLQWIQELGPWGPFFVTLFYIAACVFLLPGSVLTLAAGFLFGVPIGFLSAWLGATLGA…
A0A812NW18 339-581 None
R6GQW3 34-269 None
A0A0B9AQV1 1-211 None
Q1NVU6 7-234 None
A0A7R8H8Z7 40-240 None
A0A6U4KZU7 34-228 None
A0A842UYQ1 5-210 None
A0A1Y3WBJ7 392-576 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.