DPCstruct | MC4961

Metacluster Properties and Pfam Annotations

Number of structural domains226
Mean domain length (aa)225 ± 29 aa
Standard deviation of domain lengths29.23
Length coefficient of variation0.13
Mean AlphaFold2 pLDDT confidence score74.18
Mean fraction of residues predicted as intrinsically disordered0.25
Mean length-normalized TM-Score0.55
Mean intra-cluster local Distance Difference Test score0.57
Mean intra-cluster sequence similarity (%)18.15
Pfam Score99.49
Assigned Pfam label(s) PF06695- PF09335

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
U4KP53 3-175 None
A0A2A4I0K4 3-196 None
A0A1Y4FM91 184-406 None
A0A2W1ADE1 105-303 None
A0A7C7ESU2 10-231 None
A0A4V4MDN2 150-360 None
A0A1B0A7C6 256-509 None
A0A3Q0IUA6 40-254 None
A0A1N7FY92 1-223 None
A0A1V4WQV5 2-187 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.