DPCstruct | MC4952

Metacluster Properties and Pfam Annotations

Number of structural domains292
Mean domain length (aa)195 ± 45 aa
Standard deviation of domain lengths45.43
Length coefficient of variation0.23
Mean AlphaFold2 pLDDT confidence score83.42
Mean fraction of residues predicted as intrinsically disordered0.21
Mean length-normalized TM-Score0.56
Mean intra-cluster local Distance Difference Test score0.51
Mean intra-cluster sequence similarity (%)20.76
Pfam Score99.74
Assigned Pfam label(s) CL0023- PF00445

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A2U3E9W1 742-973 None
A0A4V2EN13 196-495 None
A0A183VVT2 1-161 None
A0A813EZG5 8-251 None
A0A822YEG4 3-122 None
A0A822YLA3 13-143 None
A0A6A2XFV5 12-202 None
A0A1Y1W5Z4 109-349 None
A0A444CBL6 12-128 None
A0A0F7STE6 187-409 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.