DPCstruct | MC4952

Metacluster Properties and Pfam Annotations

Number of structural domains292
Mean domain length (aa)195 ± 45 aa
Standard deviation of domain lengths45.43
Length coefficient of variation0.23
Mean AlphaFold2 pLDDT confidence score83.42
Mean fraction of residues predicted as intrinsically disordered0.21
Mean length-normalized TM-Score0.56
Mean intra-cluster local Distance Difference Test score0.51
Mean intra-cluster sequence similarity (%)20.76
Pfam Score99.74
Assigned Pfam label(s) CL0023- PF00445

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
Q5BER3 1-127 MNEYWKDYSGDDESFWEHEWNKHGTCINTIEPTCYTDYTPQEEVVDYLQKAVDLFKTLDTYKALAAANITPSSSATYTLDEIHSALS…
A0A2K3PNE6 2-179 LAETWPASFCQTKTCISTIPSKFSIHGLWPQNNSSPQPRQCTTTKILEKELKPLKPRIANVWPSLTGNNFGLWNHEWTVHGTCSTMA…
A0A1X2I1W0 68-194 None
A0A164XXV1 2-138 None
A0A068V660 2-113 None
A0A0D8XT59 2-157 None
A0A446ITU5 4-101 None
A0A166CQ01 89-288 None
A0A446JTB0 30-199 None
A0A2I0HYQ2 34-153 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.