DPCstruct | MC4952

Metacluster Properties and Pfam Annotations

Number of structural domains292
Mean domain length (aa)195 ± 45 aa
Standard deviation of domain lengths45.43
Length coefficient of variation0.23
Mean AlphaFold2 pLDDT confidence score83.42
Mean fraction of residues predicted as intrinsically disordered0.21
Mean length-normalized TM-Score0.56
Mean intra-cluster local Distance Difference Test score0.51
Mean intra-cluster sequence similarity (%)20.76
Pfam Score99.74
Assigned Pfam label(s) CL0023- PF00445

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
D0MTE2 15-198 None
A0A2G3AQQ9 2-125 None
R1BWW8 10-258 None
A0A3S4NI10 57-236 None
A0A834TQ74 31-178 None
A0A0A7CPF8 19-274 None
A0A4Z2CKQ1 2-174 None
A0A0L0NSV4 2-218 None
A0A4Q4XCY2 150-345 None
A0A080YWB2 188-444 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.