DPCstruct | MC4952

Metacluster Properties and Pfam Annotations

Number of structural domains292
Mean domain length (aa)195 ± 45 aa
Standard deviation of domain lengths45.43
Length coefficient of variation0.23
Mean AlphaFold2 pLDDT confidence score83.42
Mean fraction of residues predicted as intrinsically disordered0.21
Mean length-normalized TM-Score0.56
Mean intra-cluster local Distance Difference Test score0.51
Mean intra-cluster sequence similarity (%)20.76
Pfam Score99.74
Assigned Pfam label(s) CL0023- PF00445

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
J4H3S4 606-824 None
A0A066X6A4 165-455 None
A0A834WRW4 13-268 None
A0A1Q5Q8U2 51-274 None
A0A0F7ZHI2 14-208 None
A0A5A7QZD5 21-240 None
A0A7J6EME7 36-280 None
A0A811P2Q7 26-250 None
A0A3S3NPG3 23-272 None
A0A5A7PE99 40-274 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.