DPCstruct | MC49033

Metacluster Properties and Pfam Annotations

Number of structural domains396
Mean domain length (aa)147 ± 32 aa
Standard deviation of domain lengths32.48
Length coefficient of variation0.22
Mean AlphaFold2 pLDDT confidence score83.78
Mean fraction of residues predicted as intrinsically disordered0.21
Mean length-normalized TM-Score0.55
Mean intra-cluster local Distance Difference Test score0.55
Mean intra-cluster sequence similarity (%)16.75
Pfam Score95.85
Assigned Pfam label(s) CL0481- PF01250- CL0093

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A1Q6YK02 38-158 None
A0A143PHP6 4-131 None
A0A378XIR1 2-111 None
A0A7W1FGN8 1-96 None
A0A4P8L8B6 42-181 None
M5ID99 3-114 None
A0A3N0ZW07 2-143 None
A0A2G0CEU6 7-171 None
A0A315QPS7 1-121 None
A0A2N1RRE1 2-151 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.