DPCstruct | MC49014

Metacluster Properties and Pfam Annotations

Number of structural domains206
Mean domain length (aa)136 ± 34 aa
Standard deviation of domain lengths34.15
Length coefficient of variation0.25
Mean AlphaFold2 pLDDT confidence score88.19
Mean fraction of residues predicted as intrinsically disordered0.22
Mean length-normalized TM-Score0.80
Mean intra-cluster local Distance Difference Test score0.76
Mean intra-cluster sequence similarity (%)32.51
Pfam Score96.67
Assigned Pfam label(s) PF17067- PF00425- PF08432- CL0261- CL0014

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A645FPI1 46-169 None
W1U2J4 57-180 None
A0A2E8REN5 128-286 None
A0A841VV60 74-187 None
A0A6F8XX59 60-190 None
A0A7S0CDG4 39-155 None
A0A534SDR2 147-269 None
R1DLI2 280-437 None
A0A5C0DTB3 15-120 None
A0A813DPS8 747-944 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.