DPCstruct | MC49014

Metacluster Properties and Pfam Annotations

Number of structural domains206
Mean domain length (aa)136 ± 34 aa
Standard deviation of domain lengths34.15
Length coefficient of variation0.25
Mean AlphaFold2 pLDDT confidence score88.19
Mean fraction of residues predicted as intrinsically disordered0.22
Mean length-normalized TM-Score0.80
Mean intra-cluster local Distance Difference Test score0.76
Mean intra-cluster sequence similarity (%)32.51
Pfam Score96.67
Assigned Pfam label(s) PF17067- PF00425- PF08432- CL0261- CL0014

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A6A2YAP0 467-572 ECNQSNVSAVDCIKAAFPGGSMTGAPKLRSMEHLDSVEGCSRGIYSGSIGFFSYNQTFDLNIVIRNFVIHGDEASIGAGGAIVALSD…
A0A7K0XAN4 13-111 IDALFSVFPAGTLSGAPKPRAMEIIELLEPTRRGLYGGAIGYFDFTGNIDACIAIRTALLHGGTAYVQAGAGLVADSDPASENEETL…
A0A807ZMB0 59-151 None
A0A7J6LF32 593-768 None
A0A6L8E7G1 41-158 None
A0A845U4K5 1-64 None
A0A7S0Y7Y5 19-139 None
A0A645J2U3 8-88 None
A0A318M3P8 252-398 None
A0A7V2UKE9 128-258 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.