DPCstruct | MC46736

Metacluster Properties and Pfam Annotations

Number of structural domains219
Mean domain length (aa)186 ± 33 aa
Standard deviation of domain lengths32.97
Length coefficient of variation0.18
Mean AlphaFold2 pLDDT confidence score82.19
Mean fraction of residues predicted as intrinsically disordered0.22
Mean length-normalized TM-Score0.44
Mean intra-cluster local Distance Difference Test score0.51
Mean intra-cluster sequence similarity (%)11.83
Pfam Score30.30
Assigned Pfam label(s) PF12991- PF11130- PF11203- PF03135

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A6N4W4D8 374-540 None
M1QQN7 130-313 None
A0A7W1SRA4 8-199 None
A0A2W4S081 2-195 None
A0A843PS67 167-272 None
A0A1Z1UUC2 152-327 None
M0NI52 60-315 None
U2ATB4 2-114 None
A0A2G3ED87 279-442 None
A0A0G4B0Q7 9-215 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.