DPCstruct | MC46736

Metacluster Properties and Pfam Annotations

Number of structural domains219
Mean domain length (aa)186 ± 33 aa
Standard deviation of domain lengths32.97
Length coefficient of variation0.18
Mean AlphaFold2 pLDDT confidence score82.19
Mean fraction of residues predicted as intrinsically disordered0.22
Mean length-normalized TM-Score0.44
Mean intra-cluster local Distance Difference Test score0.51
Mean intra-cluster sequence similarity (%)11.83
Pfam Score30.30
Assigned Pfam label(s) PF12991- PF11130- PF11203- PF03135

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A0K2RU58 34-201 LAWDEVGPTATQASWDDYRHDSAFSASWTMTGAPRGSVNSSVLSRLLAPHGDIDRKRISLLYRPMDSARAAAVVERDQNNANVRITS…
A0A395VDF0 6-181 TQNKMSVRDFVDAADVKGNFLYRKDGVILAYLRIYFYNIELMNHAERRALSNNLAAQFKADRRDFVYTTLPREVDMDQYRQSLKERH…
A0A7X8G1D5 29-229 None
A0A4R2S4N8 10-211 None
A0A2R9SPL9 71-240 None
A0A4Q5J9X0 335-570 None
W1I6K4 25-189 None
A0A7C0UKJ5 49-233 None
A0A7D5YI23 28-197 None
A0A0F9NFI8 374-567 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.