DPCstruct | MC46648

Metacluster Properties and Pfam Annotations

Number of structural domains101
Mean domain length (aa)140 ± 22 aa
Standard deviation of domain lengths21.81
Length coefficient of variation0.16
Mean AlphaFold2 pLDDT confidence score86.76
Mean fraction of residues predicted as intrinsically disordered0.18
Mean length-normalized TM-Score0.78
Mean intra-cluster local Distance Difference Test score0.75
Mean intra-cluster sequence similarity (%)32.16
Pfam Score99.32
Assigned Pfam label(s) CL0028- CL0588

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A2U1MCE4 110-253 None
A0A7J7JFU7 1104-1230 None
A0A2I0KXC9 4-117 None
T1JH30 112-252 None
H3CG59 130-220 None
A0A1S3Z0T6 33-173 None
T1GYA0 1-113 None
A0A0A9FM12 17-135 None
A0A7R9MQ12 20-142 None
A0A1Y2DKV7 175-398 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.