DPCstruct | MC46648

Metacluster Properties and Pfam Annotations

Number of structural domains101
Mean domain length (aa)140 ± 22 aa
Standard deviation of domain lengths21.81
Length coefficient of variation0.16
Mean AlphaFold2 pLDDT confidence score86.76
Mean fraction of residues predicted as intrinsically disordered0.18
Mean length-normalized TM-Score0.78
Mean intra-cluster local Distance Difference Test score0.75
Mean intra-cluster sequence similarity (%)32.16
Pfam Score99.32
Assigned Pfam label(s) CL0028- CL0588

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
W2LZD0 34-184 YSQFNVNRWPQFGSFSTANFFLPVYNNVNRCLPGDNQCIYDQKRRKANFLKLEEAHFFASPADNRIMPWQSSIFGRYSEVDTIEEIE…
A0A3Q2R0G7 44-166 ISVCDYWNDPHHRADYLSGNTFLPLLNGEKPHMFMKEWRENFLRIKKLVMIGGPDDGVITPWQSSHYGFYNASEYVVEMKNQEFYKN…
A0A395SRY9 163-308 None
A0A287Q2U8 70-198 None
A0A7C9DKR8 10-130 None
A0A1Z5S886 59-191 None
K3WY25 2-155 None
M9MGM4 161-320 None
A0A7J0FTS3 231-358 None
L8Y7H1 50-173 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.