DPCstruct | MC45854

Metacluster Properties and Pfam Annotations

Number of structural domains846
Mean domain length (aa)192 ± 35 aa
Standard deviation of domain lengths34.67
Length coefficient of variation0.18
Mean AlphaFold2 pLDDT confidence score87.32
Mean fraction of residues predicted as intrinsically disordered0.21
Mean length-normalized TM-Score0.48
Mean intra-cluster local Distance Difference Test score0.44
Mean intra-cluster sequence similarity (%)13.92
Pfam Score87.40
Assigned Pfam label(s) PF18312- CL0707- CL0509- CL0063- PF05226

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A4V6NPP3 353-510 None
A0A0H3MF67 1-132 None
A0A2C5WUB9 28-174 None
A0A136JCC3 6-260 None
A0A2N2PHJ1 177-376 None
A0A0R2AY78 2-168 None
A0A1F6M2U6 284-467 None
A0A1F6M5J4 27-210 None
A0A139IA77 481-703 None
A0A2S8GIS2 450-630 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.