DPCstruct | MC45854

Metacluster Properties and Pfam Annotations

Number of structural domains846
Mean domain length (aa)192 ± 35 aa
Standard deviation of domain lengths34.67
Length coefficient of variation0.18
Mean AlphaFold2 pLDDT confidence score87.32
Mean fraction of residues predicted as intrinsically disordered0.21
Mean length-normalized TM-Score0.48
Mean intra-cluster local Distance Difference Test score0.44
Mean intra-cluster sequence similarity (%)13.92
Pfam Score87.40
Assigned Pfam label(s) PF18312- CL0707- CL0509- CL0063- PF05226

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A444H1D9 4-191 None
A0A7J7D3G9 22-226 None
A0A366SE87 2-161 None
A0A1I4USJ3 93-264 None
A0A0B7AI53 2-139 None
A0A0V0UPR8 9-180 None
A0A453AXC5 2-203 None
A0A1Y1IVM7 136-416 None
A0A3R7FVV9 225-481 None
A0A812LR50 145-395 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.