DPCstruct | MC45324

Metacluster Properties and Pfam Annotations

Number of structural domains408
Mean domain length (aa)399 ± 107 aa
Standard deviation of domain lengths107.34
Length coefficient of variation0.27
Mean AlphaFold2 pLDDT confidence score85.66
Mean fraction of residues predicted as intrinsically disordered0.23
Mean length-normalized TM-Score0.52
Mean intra-cluster local Distance Difference Test score0.48
Mean intra-cluster sequence similarity (%)17.67
Pfam Score82.51
Assigned Pfam label(s) PF05199- CL0063- CL0559- PF00172- PF00696

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A3L6TMF8 70-307 None
A0A1W4V3H7 48-406 None
A0A2N9IZP7 99-441 None
M7SL09 1-350 None
M7SHL2 1-251 None
C3YCA6 53-481 None
A0A653A1N1 68-547 None
A0A2S7PFX7 9-305 None
A0A7W1TUP1 13-343 None
A0A2S6C3P7 448-1005 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.