DPCstruct | MC45324

Metacluster Properties and Pfam Annotations

Number of structural domains408
Mean domain length (aa)399 ± 107 aa
Standard deviation of domain lengths107.34
Length coefficient of variation0.27
Mean AlphaFold2 pLDDT confidence score85.66
Mean fraction of residues predicted as intrinsically disordered0.23
Mean length-normalized TM-Score0.52
Mean intra-cluster local Distance Difference Test score0.48
Mean intra-cluster sequence similarity (%)17.67
Pfam Score82.51
Assigned Pfam label(s) PF05199- CL0063- CL0559- PF00172- PF00696

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A811X0H5 9-415 None
A0A3M0JI14 656-1138 None
A0A2S6U3B8 42-437 None
A0A182U8T2 632-1146 None
A0A7V8YW17 44-446 None
A0A3Q7IPT1 729-1210 None
A0A4Z1JHG3 9-277 None
A0A4Z1I6F8 3-229 None
A0A7X0NVT5 65-516 None
A0A2K8QTX4 193-514 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.