DPCstruct | MC4469

Metacluster Properties and Pfam Annotations

Number of structural domains920
Mean domain length (aa)145 ± 32 aa
Standard deviation of domain lengths32.36
Length coefficient of variation0.22
Mean AlphaFold2 pLDDT confidence score86.87
Mean fraction of residues predicted as intrinsically disordered0.26
Mean length-normalized TM-Score0.50
Mean intra-cluster local Distance Difference Test score0.48
Mean intra-cluster sequence similarity (%)13.16
Pfam Score93.65
Assigned Pfam label(s) PF10615- CL0273- CL0063- CL0336- CL0027

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A2D9SLZ6 30-159 DRAELLDAARLTINSARYAALISLDHTGQPRSRTVDAFPPDENFVVWVATRPVTRKVEQIRNNPKVTLYYWHAETRSYVSIMGMATI…
H3KE64 28-173 REMTPKEALELLRRTPNAVMATADGEGRPYGVPVTVAFVEGVFYVHGTSAGGRRSSNLTENPFASLTFVVEGGWDAEPYSLFYASVI…
A0A558CTL0 9-150 None
A0A542P3L4 29-164 None
A0A0G4HNA5 24-191 None
A0A7K2Y5X3 139-265 None
A0A7S5P6L2 231-374 None
A0A535A3E8 5-157 None
A0A2I0NEN6 108-252 None
A0A1H4DPW9 157-313 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.