DPCstruct | MC4469

Metacluster Properties and Pfam Annotations

Number of structural domains920
Mean domain length (aa)145 ± 32 aa
Standard deviation of domain lengths32.36
Length coefficient of variation0.22
Mean AlphaFold2 pLDDT confidence score86.87
Mean fraction of residues predicted as intrinsically disordered0.26
Mean length-normalized TM-Score0.50
Mean intra-cluster local Distance Difference Test score0.48
Mean intra-cluster sequence similarity (%)13.16
Pfam Score93.65
Assigned Pfam label(s) PF10615- CL0273- CL0063- CL0336- CL0027

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A849IMQ4 7-156 None
A0A535A019 177-315 None
A0A1Q7WFE2 1-92 None
A0A2G3D1E0 202-346 None
A0A0E0QL84 290-448 None
A0A415LH61 354-480 None
A0A1S2Q476 2-98 None
A0A066VAH3 95-330 None
A0A6G1M2B4 21-163 None
U2SNY4 120-266 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.