DPCstruct | MC43894

Metacluster Properties and Pfam Annotations

Number of structural domains47
Mean domain length (aa)75 ± 5 aa
Standard deviation of domain lengths4.71
Length coefficient of variation0.06
Mean AlphaFold2 pLDDT confidence score90.92
Mean fraction of residues predicted as intrinsically disordered0.32
Mean length-normalized TM-Score0.83
Mean intra-cluster local Distance Difference Test score0.91
Mean intra-cluster sequence similarity (%)49.04
Pfam Score89.63
Assigned Pfam label(s) PF14374- PF00557- PF00573

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A1U8D7S5 371-445 None
A0A812KZU1 526-601 None
A0A5N4DZZ5 63-130 None
A0A7S2QGG4 108-187 None
A0A7J7JUR1 203-277 None
A0A7R9GBA8 253-322 None
A0A7J8JH85 38-108 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.