DPCstruct | MC43894

Metacluster Properties and Pfam Annotations

Number of structural domains47
Mean domain length (aa)75 ± 5 aa
Standard deviation of domain lengths4.71
Length coefficient of variation0.06
Mean AlphaFold2 pLDDT confidence score90.92
Mean fraction of residues predicted as intrinsically disordered0.32
Mean length-normalized TM-Score0.83
Mean intra-cluster local Distance Difference Test score0.91
Mean intra-cluster sequence similarity (%)49.04
Pfam Score89.63
Assigned Pfam label(s) PF14374- PF00557- PF00573

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A821MR62 2-84 QACSCIWTESAFRKSDGLYGTWRKAAFPKSNHNLPMHKVTNTDLNRILKSPESQRALRAPRKKIQRRVLKKNLRKSPRITLKL
S7MLR6 58-133 TESAFRKLDELYGTWRRAASLKSNYNLPMHKMLNTDLSRILKSPEIQRALRAPRKKIHRRVLKKNPLKNLRIMLKL
A0A7S2CUV3 43-113 None
A0A7S0DI18 25-108 None
A0A812N881 252-330 None
A0A2I3TF82 213-279 None
A0A2B4SSK7 410-485 None
A0A4Y7KUV0 77-162 None
A0A251RTF6 57-132 None
F6HC63 118-192 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.