DPCstruct | MC42687

Metacluster Properties and Pfam Annotations

Number of structural domains708
Mean domain length (aa)215 ± 43 aa
Standard deviation of domain lengths43.44
Length coefficient of variation0.20
Mean AlphaFold2 pLDDT confidence score88.32
Mean fraction of residues predicted as intrinsically disordered0.22
Mean length-normalized TM-Score0.53
Mean intra-cluster local Distance Difference Test score0.50
Mean intra-cluster sequence similarity (%)17.38
Pfam Score82.17
Assigned Pfam label(s) PF03352- PF10576- CL0236- CL0198- PF10343

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
Q2HIE3 609-848 None
A0A200R0K8 439-661 None
I0YUU2 92-335 None
A0A7V3A903 22-257 None
A0A163H2M7 825-1055 None
A0A1B8G2R1 331-653 None
A0A4P9WUU8 2-172 None
A0A354PK09 4-226 None
A0A3E3IDZ7 2-241 None
A0A7X6CS98 27-240 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.