DPCstruct | MC42687

Metacluster Properties and Pfam Annotations

Number of structural domains708
Mean domain length (aa)215 ± 43 aa
Standard deviation of domain lengths43.44
Length coefficient of variation0.20
Mean AlphaFold2 pLDDT confidence score88.32
Mean fraction of residues predicted as intrinsically disordered0.22
Mean length-normalized TM-Score0.53
Mean intra-cluster local Distance Difference Test score0.50
Mean intra-cluster sequence similarity (%)17.38
Pfam Score82.17
Assigned Pfam label(s) PF03352- PF10576- CL0236- CL0198- PF10343

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
R1FAM4 72-311 None
A0A3D1ESV2 9-194 None
A0A2I0S3R5 160-448 None
A0A507EJ28 48-288 None
A0A287JY50 74-322 None
A0A814BIJ0 72-325 None
A0A6A5L7G2 9-167 None
A0A6A5LDY4 237-416 None
A0A2U1NJ72 399-631 None
A0A4D6MKB0 2-206 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.