DPCstruct | MC4249

Metacluster Properties and Pfam Annotations

Number of structural domains71
Mean domain length (aa)220 ± 43 aa
Standard deviation of domain lengths43.37
Length coefficient of variation0.20
Mean AlphaFold2 pLDDT confidence score76.58
Mean fraction of residues predicted as intrinsically disordered0.34
Mean length-normalized TM-Score0.56
Mean intra-cluster local Distance Difference Test score0.60
Mean intra-cluster sequence similarity (%)17.46
Pfam Score65.08
Assigned Pfam label(s) PF00122- PF00690- PF12409

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
L8WLS1 223-456 None
A0A2T7ICE8 77-339 None
A0A7S0JIM0 215-417 None
W2R3J1 248-488 None
D8SFB1 80-385 None
A0A834KRZ8 27-320 None
A0A7M7NWZ4 7-213 None
A0A7J6LFZ4 479-765 None
A0A183IH01 3-170 None
A0A5E4QGQ9 28-185 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.