DPCstruct | MC4249

Metacluster Properties and Pfam Annotations

Number of structural domains71
Mean domain length (aa)220 ± 43 aa
Standard deviation of domain lengths43.37
Length coefficient of variation0.20
Mean AlphaFold2 pLDDT confidence score76.58
Mean fraction of residues predicted as intrinsically disordered0.34
Mean length-normalized TM-Score0.56
Mean intra-cluster local Distance Difference Test score0.60
Mean intra-cluster sequence similarity (%)17.46
Pfam Score65.08
Assigned Pfam label(s) PF00122- PF00690- PF12409

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
H3H9K1 10-232 None
A0A397L0A1 8-146 None
A0A1Q9DAD2 67-327 None
A0A4Y9ZVE3 123-360 None
A0A0D8Y1J3 3-205 None
A0A6G0YWW4 58-263 None
A0A4U0VTM1 300-525 None
A0A834E8F0 26-255 None
A0A4P9ZVD7 243-510 None
A0A2A2LQ96 4-212 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.