DPCstruct | MC4186

Metacluster Properties and Pfam Annotations

Number of structural domains394
Mean domain length (aa)183 ± 31 aa
Standard deviation of domain lengths30.57
Length coefficient of variation0.17
Mean AlphaFold2 pLDDT confidence score89.35
Mean fraction of residues predicted as intrinsically disordered0.20
Mean length-normalized TM-Score0.65
Mean intra-cluster local Distance Difference Test score0.58
Mean intra-cluster sequence similarity (%)20.51
Pfam Score92.24
Assigned Pfam label(s) PF02769- PF02142- CL0063- PF21553- CL0123

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A3M6UXK9 37-207 None
A0A5C6M566 5-153 None
Q871G5 41-251 None
A0A3M9VTE2 88-283 None
A0A694A4F9 450-632 None
A0A378FQG0 2-124 None
A0A848SQS0 2-112 None
A0A5N6L2B2 28-259 None
A0A5N6KQ71 1000-1215 None
A0A5C8APX6 4-145 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.