DPCstruct | MC4186

Metacluster Properties and Pfam Annotations

Number of structural domains394
Mean domain length (aa)183 ± 31 aa
Standard deviation of domain lengths30.57
Length coefficient of variation0.17
Mean AlphaFold2 pLDDT confidence score89.35
Mean fraction of residues predicted as intrinsically disordered0.20
Mean length-normalized TM-Score0.65
Mean intra-cluster local Distance Difference Test score0.58
Mean intra-cluster sequence similarity (%)20.51
Pfam Score92.24
Assigned Pfam label(s) PF02769- PF02142- CL0063- PF21553- CL0123

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
G7V6A0 12-229 None
A0A225ZK38 23-153 None
A0A4U0XRZ5 3-185 None
A0A7X2IEJ2 12-203 None
A0A0F7PS90 3-184 None
A0A2E7CKM1 9-205 None
A0A3D3ULQ8 150-343 None
A0A815LM68 401-606 None
A0A815J235 143-280 None
A0A2T4XC22 8-182 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.