DPCstruct | MC40477

Metacluster Properties and Pfam Annotations

Number of structural domains624
Mean domain length (aa)75 ± 11 aa
Standard deviation of domain lengths11.48
Length coefficient of variation0.15
Mean AlphaFold2 pLDDT confidence score84.76
Mean fraction of residues predicted as intrinsically disordered0.24
Mean length-normalized TM-Score0.76
Mean intra-cluster local Distance Difference Test score0.71
Mean intra-cluster sequence similarity (%)28.82
Pfam Score99.41
Assigned Pfam label(s) CL0220- CL0022

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A524QZ71 351-426 None
A0A1V5MLW6 369-443 None
A0A1V5MM98 30-96 None
A0A1V5MMV9 377-441 None
A0A7X9IEB2 543-611 None
A0A7X9IEL8 281-345 None
A0A7X9IG19 31-103 None
A0A7C3LH53 231-316 None
A0A7C3LJ05 372-447 None
A0A7C3LMJ0 313-396 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.