DPCstruct | MC40477

Metacluster Properties and Pfam Annotations

Number of structural domains624
Mean domain length (aa)75 ± 11 aa
Standard deviation of domain lengths11.48
Length coefficient of variation0.15
Mean AlphaFold2 pLDDT confidence score84.76
Mean fraction of residues predicted as intrinsically disordered0.24
Mean length-normalized TM-Score0.76
Mean intra-cluster local Distance Difference Test score0.71
Mean intra-cluster sequence similarity (%)28.82
Pfam Score99.41
Assigned Pfam label(s) CL0220- CL0022

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A7C0WC75 540-609 DACDWVCGDPDADGRINILDITYIVSYLYKGGSAPDPIESADVNGSGSINILDVTYIVNYLYKGGPEPDC
A0A2R2JFJ7 2-65 PGDVDGNGSINSIDFALMRNYLLGNLKDFPAEDDIKAGDLNGDKSININDFAIMRMYLLGMITK
A0A2D8N049 396-482 None
A0A2D8N044 349-441 None
A0A2D8MWJ4 50-145 None
A0A2D8N0W1 1122-1213 None
A0A2D8MX19 8-88 None
A0A2D8N1P9 32-124 None
B8I4T1 375-448 None
A0A1E3C487 478-546 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.